The Sporothrix schenckii 1099-18 genome sequence and gene models were not determined by the Joint Genome Institute (JGI) but were downloaded from Ensembl Fungi on Apr 11, 2020. Please note that this copy of the genome is not maintained by Ensembl and is therefore not automatically updated. In order to allow comparative analyses with other fungal genomes sequenced by the JGI, a copy of this genome is incorporated into MycoCosm. The JGI Annotation Pipeline was used to add the functional annotation to this genome.
Sporothrix schenckii is found in soil and on living and decomposing plant material such as peat moss worldwide. It can infect humans as well as animals causing sporotrichosis, commonly known as "rose handler's disease." The most common route of infection is the introduction of spores to the body through a cut or puncture wound in the skin. Infection commonly occurs in otherwise healthy individuals but is rarely life-threatening and can be treated with antifungals. When in the environment or grown in the laboratory at 25 °C (77 °F) it is found growing as filamentous hyphae. At 37 °C (99 °F) either in the laboratory or in host tissue, it assumes its yeast form. The transition between the hyphal and yeast forms is temperature dependent making S. schenckii a thermally dimorphic fungus.
Genome Reference(s)
Teixeira MM, de Almeida LG, Kubitschek-Barreira P, Alves FL, Kioshima ES, Abadio AK, Fernandes L, Derengowski LS, Ferreira KS, Souza RC, Ruiz JC, de Andrade NC, Paes HC, Nicola AM, Albuquerque P, Gerber AL, Martins VP, Peconick LD, Neto AV, Chaucanez CB, Silva PA, Cunha OL, de Oliveira FF, dos Santos TC, Barros AL, Soares MA, de Oliveira LM, Marini MM, Villalobos-Duno H, Cunha MM, de Hoog S, da Silveira JF, Henrissat B, NiƱo-Vega GA, Cisalpino PS, Mora-Montes HM, Almeida SR, Stajich JE, Lopes-Bezerra LM, Vasconcelos AT, Felipe MS
Comparative genomics of the major fungal agents of human and animal Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.
BMC Genomics. 2014 Oct 29;15():943. doi: 10.1186/1471-2164-15-943